Ethanol → HCID 69216007, compound

Participants

Reaction Steps

To a solution of methyl 4-{4-[(4-formyl-2-methoxyphenoxy)methyl]-5-methyl-1,3-oxazol-2-yl}benzoate (0.92 g) in tetrahydrofuran (20 mL)-ethanol (10 mL) was gradually added sodium borohydride (0.09 g) at room temperature. After stirring the reaction mixture for 1 hr, water was added, and the precipitated crystals were collected by filtration to give methyl 4-{4-[(4-hydroxymethyl-2-methoxyphenoxy)methyl]-5-methyl-1,3-oxazol-2-yl}benzoate as colorless crystals (0.83 g, yield 90%). Recrystallization from ethyl acetate-hexane gave colorless prism crystals. melting point: 170-171° C.

Provenance & Evidence