Ethanol → HCID 69215991, compound

Participants

Reaction Steps

To a solution of 3-methoxy-4-[(5-methyl-2-phenyl-1,3-thiazol-4-yl)methoxy]benzaldehyde (1.15 g) in tetrahydrofuran (10 mL)-ethanol (10 mL) was gradually added sodium borohydride (0.13 g) at room temperature. After stirring the reaction mixture for 2 hrs, water was added, and the precipitated crystals were collected by filtration to give {3-methoxy-4-[(5-methyl-2-phenyl-1,3-thiazol-4-yl)methoxy]phenyl}methanol as colorless crystals (1.05 g, yield 91%). Recrystallization from ethyl acetate-hexane gave colorless prism crystals. melting point: 134-135° C.

Provenance & Evidence