Triphenylphosphine → HCID 10884647, compound

Participants

Reaction Steps

A mixture of 4-chloromethyl-2-isopropyl-1,3-thiazole (6.30 g), triphenylphosphine (9.42 g) and acetonitrile (200 mL) was heated under reflux for 15 hrs. After concentration of the reaction mixture, the precipitated crystals were washed with diethyl ether to give [(2-isopropyl-1,3-thiazol-4-yl)methyl]triphenylphosphonium chloride as colorless crystals (13.21 g, yield 84%). Recrystallization from acetonitrile-diethyl ether gave colorless prism crystals. melting point: 246-247° C.

Provenance & Evidence