Ethanol → HCID 69214329, compound

Participants

Reaction Steps

To a solution of 3-({4-[(2-phenyl-5-methyl-1,3-oxazol-4-yl)methoxy]benzyl}oxy)-1-phenyl-1H-pyrazole-4-carbaldehyde (0.50 g) in tetrahydrofuran (5 mL)-ethanol (10 mL) was gradually added sodium borohydride (0.040 g) at 0° C. After stirring the reaction mixture at room temperature for 1 hr, water was added, and the precipitated crystals were collected by filtration to give [3-({4-[(2-phenyl-5-methyl-1,3-oxazol-4-yl)methoxy]benzyl}oxy)-1-phenyl-1H-pyrazol-4-yl]methanol as colorless crystals (0.50 g, yield 98%). Recrystallization from ethyl acetate-hexane gave colorless prism crystals. melting point: 118-119° C.

Provenance & Evidence