HCID 69217132, compound → HCID 86605890, compound

Participants

Reaction Steps

A mixture of {4-[(4-{[2-(2-furyl)-5-methyl-1,3-oxazol-4-yl]methoxy}-3-methoxybenzyl)oxy]-2-phenylpyrimidin-5-yl}methanol (2.10 g), activated manganese dioxide (8.40 g) and tetrahydrofuran (80 mL) was stirred at room temperature for 3 hrs. Manganese dioxide was removed by filtration, and the filtrate was concentrated. Recrystallization of the obtained crystal from ethyl acetate-hexane gave 4-[(4-{[2-(2-furyl)-5-methyl-1,3-oxazol-4-yl]methoxy}-3-methoxybenzyl)oxy]-2-phenylpyrimidine-5-carbaldehyde as colorless prism crystals (1.50 g, yield 72%). melting point: 143-144° C.

Provenance & Evidence