4-Methoxy-7-morpholinobenzo[d]thiazol-2-amine → HCID 11525354, compound

HRID 2222086Notes

Reaction equation

HRID 2222086 reaction equation
[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH2:12])[S:11][C:7]=2[C:6]([N:13]2[CH2:18][CH2:17][O:16][CH2:15][CH2:14]2)=[CH:5][CH:4]=1.C1([O:25][C:26]([C:28]2[N:29]([CH3:39])[C:30]([CH2:33][N:34]3[CH2:38][CH2:37][CH2:36][CH2:35]3)=[N:31][CH:32]=2)=O)C=CC=CC=1>>[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH:12][C:26]([C:28]3[N:29]([CH3:39])[C:30]([CH2:33][N:34]4[CH2:38][CH2:37][CH2:36][CH2:35]4)=[N:31][CH:32]=3)=[O:25])[S:11][C:7]=2[C:6]([N:13]2[CH2:18][CH2:17][O:16][CH2:15][CH2:14]2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 114028614-Methoxy-7-morpholinobenzo[d]thiazol-2-amineHCID 58592606HCID 58592606, compound

Product 1

HCID 11525354HCID 11525354, compound

Procedure

Using 4-methoxy-7-morpholin-4-yl-benzothiazol-2-ylamine and 3-methyl-2-pyrrolidin-1-ylmethyl-3H-imidazole-4-carboxylic acid phenyl ester, the title compound was obtained as off-white solid (76% yield). MS: m/e=457(M+H+), mp 255° C.

Sources & evidence

ORD record
ord-2cddda40c5424885bc16e41933d4e18d
Source dataset
uspto-grants-2008_05
Patent number
US07371749B2

Reaction notes

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