4-Methoxy-7-morpholinobenzo[d]thiazol-2-amine → HCID 11619458, compound

HRID 2222087Notes

Reaction equation

HRID 2222087 reaction equation
[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH2:12])[S:11][C:7]=2[C:6]([N:13]2[CH2:18][CH2:17][O:16][CH2:15][CH2:14]2)=[CH:5][CH:4]=1.C([O:21][C:22]([C:24]1[CH:25]=[N:26][N:27]([CH2:29][CH2:30][N:31]2[CH2:35][CH2:34][CH2:33][CH2:32]2)[CH:28]=1)=O)C>>[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH:12][C:22]([C:24]3[CH:25]=[N:26][N:27]([CH2:29][CH2:30][N:31]4[CH2:35][CH2:34][CH2:33][CH2:32]4)[CH:28]=3)=[O:21])[S:11][C:7]=2[C:6]([N:13]2[CH2:18][CH2:17][O:16][CH2:15][CH2:14]2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 114028614-Methoxy-7-morpholinobenzo[d]thiazol-2-amineHCID 58592597HCID 58592597, compound

Product 1

HCID 11619458HCID 11619458, compound

Procedure

Using 4-methoxy-7-morpholin-4-yl-benzothiazol-2-ylamine and 1-(2-pyrrolidin-1-yl-ethyl)-1H-pyrazole-4-carboxylic acid ethyl ester, the title compound was obtained as white solid (13% yield). MS: m/e=457(M+H+), mp 190-192° C.

Sources & evidence

ORD record
ord-c5e87a7177134690a4f4fa0cf221acb7
Source dataset
uspto-grants-2008_05
Patent number
US07371749B2

Reaction notes

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