2-Methoxyisonicotinic Acid → HCID 11750364, compound
Reaction equation
[O:1]1[CH2:7][CH:6]([C:8]2[C:16]3[S:15][C:14]([NH2:17])=[N:13][C:12]=3[C:11]([O:18][CH3:19])=[CH:10][CH:9]=2)[CH2:5][O:4][CH2:3][CH2:2]1.[CH3:20][O:21][C:22]1[CH:23]=[C:24]([CH:28]=[CH:29][N:30]=1)[C:25](O)=[O:26]>>[O:4]1[CH2:5][CH:6]([C:8]2[C:16]3[S:15][C:14]([NH:17][C:25](=[O:26])[C:24]4[CH:28]=[CH:29][N:30]=[C:22]([O:21][CH3:20])[CH:23]=4)=[N:13][C:12]=3[C:11]([O:18][CH3:19])=[CH:10][CH:9]=2)[CH2:7][O:1][CH2:2][CH2:3]1Participants
3
Procedure
Using 7-[1,4]dioxepan-6-yl-4-methoxy-benzothiazol-2-ylamine and 2-methoxy-isonicotinic acid, the title compound was prepared. MS: m/e=416(M+H+). Following the general method of example 1 the compounds of examples 17 to 34 were prepared.
Workup
- customwere prepared
Sources & evidence
- ORD record
- ord-a00e4920d32e4ab7a146a0ebcc1a1ec3
- Source dataset
- uspto-grants-2008_05
- Patent number
- US07371748B2
Reaction notes
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