HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenyl chloroformate → (1S,4S)-2-Oxa-5-aza-bicyclo[2.2.1]heptane-5-carboxylic acid (7-[1,4]dioxepan-6-yl-4-methoxy-benzothiazol-2-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenyl chloroformate | HCID 15891 | — |
| Reactant | (1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptane hydrobromide | HCID 11159293 | — |
| Reactant | 7-[1,4]Dioxepan-6-yl-4-methoxy-benzothiazol-2-ylamine | HCID 59711805 | — |
| Product | (1S,4S)-2-Oxa-5-aza-bicyclo[2.2.1]heptane-5-carboxylic acid (7-[1,4]dioxepan-6-yl-4-methoxy-benzothiazol-2-yl)-amide | HCID 86595140 | — |
Reaction Steps
Using 7-[1,4]dioxepan-6-yl-4-methoxy-benzothiazol-2-ylamine, phenyl chloroformate and (1S,4S)-2oxa-5-aza-bicyclo[2.2.1]heptane, the title compound was prepared as off-white solid. MS: m/e=422(M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07371748B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-7b6872b148de43b7a569c92c22f83a7b |
| Source note | uspto-grants-2008_05 |