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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2222161Generated: October 25, 2026

Phenyl chloroformate → 1-Oxa-8-aza-spiro[4.5]decane-8-carboxylic acid (7-[1,4]dioxepan-6-yl-4-methoxy-benzothiazol-2-yl)-amide

https://huagongshe.com/reaction/2222161

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenyl chloroformateHCID 15891—
Reactant1-Oxa-8-azaspiro(4.5)decaneHCID 21934982—
Reactant7-[1,4]Dioxepan-6-yl-4-methoxy-benzothiazol-2-ylamineHCID 59711805—
Product1-Oxa-8-aza-spiro[4.5]decane-8-carboxylic acid (7-[1,4]dioxepan-6-yl-4-methoxy-benzothiazol-2-yl)-amideHCID 86595142—

Reaction Steps

Using 7-[1,4]dioxepan-6-yl-4-methoxy-benzothiazol-2-ylamine, phenyl chloroformate and 1-oxa-8-aza-spiro[4.5]decane, the title compound was prepared as light brown powder. MS: m/e=448(M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07371748B2
Source datasetuspto-grants-2008_05
ORD IDord-ce4add4577c14c8db6746b3cb8e384a5
Source noteuspto-grants-2008_05