HCID 22283057, compound → 7-[1,4]Dioxepan-6-yl-4-methoxy-benzothiazol-2-ylamine

HRID 2222180Notes

Reaction equation

HRID 2222180 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:15][O:14][CH2:13][CH2:12][O:11][CH2:10]2)=[CH:5][C:4]=1[N+:16]([O-])=O.COC1C2[N:27]=[C:28](N)[S:29]C=2C(OC2C=CC=CC=2)=CC=1>>[O:14]1[CH2:15][CH:9]([C:6]2[C:5]3[S:29][C:28]([NH2:27])=[N:16][C:4]=3[C:3]([O:2][CH3:1])=[CH:8][CH:7]=2)[CH2:10][O:11][CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 22283057HCID 22283057, compoundHCID 59711802HCID 59711802, compound

Product 1

HCID 597118057-[1,4]Dioxepan-6-yl-4-methoxy-benzothiazol-2-ylamineYield 57%

Procedure

The title compound was prepared from 6-(4-methoxy-3-nitro-phenyl)-1,4-dioxepane in exact the same manner as described in WO01/97786 for 4-methoxy-7-phenoxy-benzothiazol-2-yl-amine in 57% yield (3.7 g). MS: m/e=281(M+H+).

Sources & evidence

ORD record
ord-9cf583d45a7f4420b5ddeb10e4bfb219
Source dataset
uspto-grants-2008_05
Patent number
US07371748B2

Reaction notes

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