3,4-Dimethoxybenzeneacetonitrile → HCID 23362299, compound

HRID 2222339Notes

Reaction equation

HRID 2222339 reaction equation
[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=O)=[CH:4][CH:3]=1.[CH3:10][O:11][C:12]1[CH:13]=[C:14]([CH:18]=[CH:19][C:20]=1[O:21][CH3:22])[CH2:15][C:16]#[N:17]>>[CH3:10][O:11][C:12]1[CH:13]=[C:14](/[C:15](=[CH:6]/[C:5]2[CH:8]=[CH:9][C:2]([F:1])=[CH:3][CH:4]=2)/[C:16]#[N:17])[CH:18]=[CH:19][C:20]=1[O:21][CH3:22]

Participants

3

Reactant 2

HCID 667273,4-DimethoxybenzeneacetonitrileHCID 680234-Fluorobenzaldehyde

Product 1

HCID 23362299HCID 23362299, compoundYield 72.5%

Procedure

4-Fluorobenzaldehyde (620 mg) and 3,4-dimethoxybenzyl cyanide (880 mg) were subjected to condensation in accordance with process A of (production process 2), to thereby produce the target product (1.02 g, yield: 72%).

Sources & evidence

ORD record
ord-afd66124acc44f5281578f1222d778d6
Source dataset
uspto-grants-2008_05
Patent number
US07371773B2

Reaction notes

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