3,4-Dimethoxybenzeneacetonitrile → HCID 10357487, compound

HRID 2222343Notes

Reaction equation

HRID 2222343 reaction equation
[F:1][C:2]1[C:9]([F:10])=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=O.[CH3:11][O:12][C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][C:21]=1[O:22][CH3:23])[CH2:16][C:17]#[N:18]>>[F:1][C:2]1[C:9]([F:10])=[CH:8][CH:7]=[CH:6][C:3]=1/[CH:4]=[C:16](/[C:15]1[CH:19]=[CH:20][C:21]([O:22][CH3:23])=[C:13]([O:12][CH3:11])[CH:14]=1)\[C:17]#[N:18]

Participants

3

Reactant 2

HCID 667273,4-DimethoxybenzeneacetonitrileHCID 1376642,3-Difluorobenzaldehyde

Product 1

HCID 10357487HCID 10357487, compoundYield 90%

Procedure

2,3-Difluorobenzaldehyde (426 mg) and 3,4-dimethoxybenzyl cyanide (532 mg) were subjected to condensation in accordance with process A of (production process 2), to thereby produce the target product (813 mg, yield: 90%).

Sources & evidence

ORD record
ord-0044fba3bf5e442f8a00e95cc9e368b9
Source dataset
uspto-grants-2008_05
Patent number
US07371773B2

Reaction notes

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