3,4-Dimethoxybenzeneacetonitrile → HCID 10426075, compound

HRID 2222348Notes

Reaction equation

HRID 2222348 reaction equation
[F:1][C:2]1[C:9]([F:10])=[C:8]([F:11])[CH:7]=[CH:6][C:3]=1[CH:4]=O.[CH3:12][O:13][C:14]1[CH:15]=[C:16]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[CH2:17][C:18]#[N:19]>>[CH3:12][O:13][C:14]1[CH:15]=[C:16](/[C:17](=[CH:4]/[C:3]2[CH:6]=[CH:7][C:8]([F:11])=[C:9]([F:10])[C:2]=2[F:1])/[C:18]#[N:19])[CH:20]=[CH:21][C:22]=1[O:23][CH3:24]

Participants

3

Reactant 2

HCID 667273,4-DimethoxybenzeneacetonitrileHCID 5192262,3,4-Trifluorobenzaldehyde

Product 1

HCID 10426075HCID 10426075, compoundYield 30%

Procedure

2,3,4-Trifluorobenzaldehyde (160 mg) and 3,4-dimethoxybenzyl cyanide (177 mg) were subjected to condensation in accordance with process B of (production process 2), to thereby produce the target product (90 mg, yield: 30%).

Sources & evidence

ORD record
ord-90755235e24d4aa4a50f6e191f048e5f
Source dataset
uspto-grants-2008_05
Patent number
US07371773B2

Reaction notes

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