3,4-Dimethoxybenzeneacetonitrile → HCID 10246936, compound

HRID 2222359Notes

Reaction equation

HRID 2222359 reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=O)=[CH:4][C:3]=1[N+:10]([O-:12])=[O:11].[CH3:13][O:14][C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][C:23]=1[O:24][CH3:25])[CH2:18][C:19]#[N:20]>>[Cl:1][C:2]1[CH:9]=[CH:8][C:5](/[CH:6]=[C:18](/[C:17]2[CH:21]=[CH:22][C:23]([O:24][CH3:25])=[C:15]([O:14][CH3:13])[CH:16]=2)\[C:19]#[N:20])=[CH:4][C:3]=1[N+:10]([O-:12])=[O:11]

Participants

3

Reactant 2

HCID 667273,4-DimethoxybenzeneacetonitrileHCID 855054-Chloro-3-nitrobenzaldehyde

Product 1

HCID 10246936HCID 10246936, compoundYield 36%

Procedure

4-Chloro-3-nitrobenzaldehyde (557 mg) and 3,4-dimethoxybenzyl cyanide (532 mg) were subjected to condensation in accordance with process B of (production process 2), to thereby produce the target product (372 mg, yield: 36%).

Sources & evidence

ORD record
ord-f7ce698494e64687bacaa692871ca644
Source dataset
uspto-grants-2008_05
Patent number
US07371773B2

Reaction notes

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