3,4-Dimethoxybenzeneacetonitrile → HCID 10087867, compound

HRID 2222360Notes

Reaction equation

HRID 2222360 reaction equation
[F:1][C:2]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:3]=1[CH:4]=O.[CH3:13][O:14][C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][C:23]=1[O:24][CH3:25])[CH2:18][C:19]#[N:20]>>[CH3:13][O:14][C:15]1[CH:16]=[C:17](/[C:18](=[CH:4]/[C:3]2[CH:6]=[C:7]([N+:10]([O-:12])=[O:11])[CH:8]=[CH:9][C:2]=2[F:1])/[C:19]#[N:20])[CH:21]=[CH:22][C:23]=1[O:24][CH3:25]

Participants

3

Reactant 2

HCID 667273,4-DimethoxybenzeneacetonitrileHCID 27347702-Fluoro-5-nitrobenzaldehyde

Product 1

HCID 10087867HCID 10087867, compoundYield 15%

Procedure

2-Fluoro-5-nitrobenzaldehyde (85 mg) and 3,4-dimethoxybenzyl cyanide (89 mg) were subjected to condensation in accordance with process B of (production process 2), to thereby produce the target product (24 mg, yield: 15%).

Sources & evidence

ORD record
ord-82ffbd5f61af414f94c8b34b7a19b9a9
Source dataset
uspto-grants-2008_05
Patent number
US07371773B2

Reaction notes

Loading…