Veratraldehyde → HCID 23089836, compound

Participants

Reaction Steps

The hydroxyl group of 4-hydroxybenzyl cyanide (26.63 g) was protected by use of 2-methoxyethoxymethyl chloride (24.42 g) in accordance with (production process 1), to thereby produce an MEM form (24.39 g, yield: 55%). The resultant MEM form (22.13 g) and 3,4-dimethoxybenzaldehyde (16.62 g) were subjected to condensation in accordance with process A of (production process 2), to thereby produce the target product (29.79 g, yield: 81%).

Provenance & Evidence