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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2222367Generated: October 29, 2026

(Z)-2-(3,4-dimethoxyphenyl)-3-(4-hydroxyphenyl)acrylonitrile → (E)-2-(3,4-dimethoxy-phenyl)-3-(4-hydroxy-phenyl)-acrylonitrile

https://huagongshe.com/reaction/2222367

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(Z)-2-(3,4-dimethoxyphenyl)-3-(4-hydroxyphenyl)acrylonitrileHCID 10446442—
SolventAcetonitrileHCID 6342—
Product(E)-2-(3,4-dimethoxy-phenyl)-3-(4-hydroxy-phenyl)-acrylonitrileHCID 3914914241%

Reaction Steps

Compound 1 (100 mg) was dissolved in acetonitrile, and the resultant solution was subjected to photoreaction by use of a high-pressure mercury lamp. The resultant reaction mixture was concentrated to dryness under reduced pressure, followed by purification by use of a silica gel column, to thereby produce the target product (41 mg, yield: 41%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07371773B2
Source datasetuspto-grants-2008_05
ORD IDord-89bde775fc994b5aa80b2fa5945a3ae0
Source noteuspto-grants-2008_05