Acetic Anhydride → HCID 69270220, compound

HRID 2222381Notes

Reaction equation

HRID 2222381 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4](/[CH:8]=[C:9](/[C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[C:14]([O:20][CH3:21])[CH:13]=2)\[C:10]#[N:11])[CH:5]=[CH:6][CH:7]=1.[C:22](OC(=O)C)(=[O:24])[CH3:23]>N1C=CC=CC=1>[C:10]([C:9]([C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[C:14]([O:20][CH3:21])[CH:13]=1)=[CH:8][C:4]1[CH:3]=[C:2]([NH:1][C:22](=[O:24])[CH3:23])[CH:7]=[CH:6][CH:5]=1)#[N:11]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 9995865HCID 9995865, compound

Product 1

HCID 69270220HCID 69270220, compoundYield 84%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Compound 57 (50 mg) was acetylated with acetic anhydride and pyridine in accordance with a customary method, to thereby produce the target product (48 mg, yield: 84%).

Sources & evidence

ORD record
ord-54276fc159194f08821a09ce477fddd7
Source dataset
uspto-grants-2008_05
Patent number
US07371773B2

Reaction notes

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