HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminoindole → 6-Cyano-4-(indol-5-ylamino)-7-(2-(1,2,3-triazol-1-yl)ethoxy)quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminoindole | HCID 78867 | — |
| Reactant | 4-Chloro-6-cyano-7-(2-(1,2,3-triazol-1-yl)ethoxy)quinoline | HCID 59712235 | — |
| Product | 6-Cyano-4-(indol-5-ylamino)-7-(2-(1,2,3-triazol-1-yl)ethoxy)quinoline | HCID 10294088 | 93.6% |
Reaction Steps
Using an analogous procedure to that described in Example 1, 4-chloro-6-cyano-7-(2-(1,2,3-triazol-1-yl)ethoxy)quinoline (60 mg, 0.2 mmol) was reacted with 5-aminoindole (32 mg, 0.25 mmol) to give 6-cyano-4-(indol-5-ylamino)-7-(2-(1,2,3-triazol-1-yl)ethoxy)quinoline (74 mg, 86%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07371765B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-2d1756f142bd4b70afed49d397a49511 |
| Source note | uspto-grants-2008_05 |