4-fluoro-2-methyl-1H-indol-5-ol → HCID 10111016, compound

Participants

Reaction Steps

Using an analogous procedure to that described in Example 12, 4-chloro-6-cyano-7-(2-methoxyethoxy)quinoline (200 mg, 0.76 mmol) was reacted with 4-fluoro-5-hydroxy-2-methylindole (150 mg, 0.91 mmol), (prepared as described for the starting material in Example 11), in DMF (6 ml) to give 6-cyano-4-(4-fluoro-2-methylindol-5-yloxy)-7-(2-methoxyethoxy)quinoline (170 mg, 57%).

Provenance & Evidence