反应详情

Using an analogous procedure to that described for the preparation of the starting material in Example 15 (see note a) above), 4-chloro-6-cyano-7-hydroxyquinoline (300 mg, 1.46 mmol), (prepared as described for the starting material in Example 1), was reacted with 3-(1,2,3-triazol-1-yl)propan-1-ol (242 mg, 1.9 mmol) to give 4chloro-6-cyano-7-(3-(1,2,3-triazol-1-yl)propoxy)quinoline (349 mg, 86%).

1. customthat described for the preparation of the starting material in Example 15 (
2. custom(prepared