HCID 59712343, compound → HCID 59712400, compound

Participants

Reaction Steps

To a solution of 3.69 g of methyl 2-[(acetyloxy)(2-oxo-1,2-dihydro-4-pyridinyl)methyl]tetrahydro-2-furancarboxylate in 30 ml of acetic acid was added 8.17 g of zinc, and the mixture was heated under reflux for 24 hours. This procedure was repeated twice. The reaction mixture was cooled, filtered through Celite, and the Celite and the filtrate were washed with ethanol. The combined organic layers were evaporated, and the residue was purified by silica gel column chromatography, to give 1.31 g of the title compound as a colorless oil.

Provenance & Evidence