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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2222504Generated: October 30, 2026

4-Methylmorpholine → HCID 178492727, compound

https://huagongshe.com/reaction/2222504

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylmorpholineHCID 7972—
ReactantO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
Reactant(S)-1-(5-chloro-1H-benzimidazol-2-yl)ethylamineHCID 42034613—
Reactant3-Methoxy-4-(piperidin-2-on-1-yl)benzoic acidHCID 67049343—
SolventDimethylformamideHCID 6228—
ProductHCID 178492727HCID 178492727—

Reaction Steps

Prepared analogously to Example 1f from 3-methoxy-4-(piperidin-2-on-1-yl)-benzoic acid, TBTU, NMM and (1S)-1-(5-chloro-1H-benzimidazol-2-yl)ethylamine in DMF and subsequent purification by preparative HPLC.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07371743B2
Source datasetuspto-grants-2008_05
ORD IDord-934fb3738e8447e59162062437ab0c25
Source noteuspto-grants-2008_05