Phthalimide → HCID 69101410, compound

Participants

Reaction Conditions

Reaction Steps

1-Hydroxy-1-(4-pyridinyl)-10-phthalimidodecane (1 equiv.) is dissolved in THF with stirring. Phthalimide (1.5 equiv.) and triphenylphosphine (2.1 equiv.) are added to the solution and the resulting mixture is cooled to 0° C. Diisopropyl azodicarboxylate (2.0 equiv.) is added dropwise to the above solution and the reaction is stirred until completion. The resulting solid is filtered off and the filtrate is concentrated in vacuo. The crude product is purified by silica gel chromatography to yield 1,10-diphthalimido-1-pyridinyldecane.

Provenance & Evidence