HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 58664770, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | Bis(2-amino-1H-imidazole) sulphate | HCID 135136 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | HCID 58664775 | HCID 58664775 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 58664770 | HCID 58664770 | — |
Reaction Steps
4.6 g of potassium carbonate are added to a solution of 10 g of 9, 4.4 g of 2-aminoimidazole sulfate, 9.26 g of TBTU and 0.9 g of HOBt in 100 ml of absolute DMF, and the mixture is stirred at 700 under nitrogen for 16 hours. The mixture is cooled to room temperature, poured into 750 ml of cold water, the precipitate is separated off, washed with cold water and dried. The crude product is treated with hot acetonitrile and filtered off after cooling. The residue is recrystallised from ethanol, giving 10.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07371854B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-b9d5eec26f8c4b48bf69455578091ebe |
| Source note | uspto-grants-2008_05 |