Water → HCID 178476383, compound

HRID 2222998Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]=[CH:10][C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=2)=[O:12])=[CH:5][CH:4]=1.S(O)(O)(=O)=[O:20].[NH2:24][C:25]1[C:26](O)=[N:27][N:28]([CH2:30][CH3:31])[CH:29]=1.[OH2:33]>C(O)(=O)C>[C:11]([O-:20])(=[O:12])[CH3:13].[CH2:30]([N:28]1[C:29]([OH:33])=[C:25](/[N:24]=[C:11]2\[CH:10]=[C:9]([C:6]3[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=3)[N+:14]3[C:13]\2=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH:26]=[N:27]1)[CH3:31]

Participants

Conditions

Temperature: 50 °C

Procedure

0.12 g 2-[3-(4-methoxyphenyl)-1-oxoprop-2-enyl]pyridine and 0.11 g 4-amino-1-ethyl-hydroxy-1H-pyrazol-sulfate (1:1) are agitated in 3 ml glacial acetic acid for 1 hour at room temperature and then agitated for 2 hours at 50° C. Water (20 ml) is added, setting the pH value to about 5. Subsequently, the violet precipitate is filtered, washed with 2×5 ml water, and dried in a vacuum.

Workup

filtrationSubsequently, the violet precipitate is filtered
washwashed with 2×5 ml water
customdried in a vacuum

Sources & evidence

ORD record: ord-7bc04b2279d141009356a2404adfcc0d
Source dataset: uspto-grants-2008_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07374583B2

Reaction notes

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