HRID2223103

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID392871

1-(tert-Butoxycarbonyl)-4-piperidinecarboxylic acid

C11H19NO4

结构：CC(C)(CN)c1cc(-c2ccc(Cl)c(O)c2)c(-c2ccncc2)o1

HCID10291125

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N1CCC(C(=O)NCC(C)(C)c2cc(-c3ccc(Cl)c(O)c3)c(-c3ccncc3)o2)CC1

HCID69139022

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from the product of Example 7 Step 2 and N—BOC-isonipecotic acid as described in Example 4 Step 3; MS (ES+) m/e 554, 556 [M+H]+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-22165e97385e4af189f9661b9463efb2
来源数据集: uspto-grants-2008_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07375105B2
来源说明: uspto-grants-2008_05

反应 SMILES

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([C:19]([CH3:23])([CH3:22])[CH2:20][NH2:21])[O:11][C:12]=2[C:13]2[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=2)=[CH:4][C:3]=1[OH:24].[C:25]([N:32]1[CH2:40][CH2:39][CH:35]([C:36](O)=[O:37])[CH2:34][CH2:33]1)([O:27][C:28]([CH3:31])([CH3:30])[CH3:29])=[O:26]>>[C:28]([O:27][C:25]([N:32]1[CH2:40][CH2:39][CH:35]([C:36](=[O:37])[NH:21][CH2:20][C:19]([C:10]2[O:11][C:12]([C:13]3[CH:14]=[CH:15][N:16]=[CH:17][CH:18]=3)=[C:8]([C:5]3[CH:6]=[CH:7][C:2]([Cl:1])=[C:3]([OH:24])[CH:4]=3)[CH:9]=2)([CH3:22])[CH3:23])[CH2:34][CH2:33]1)=[O:26])([CH3:31])([CH3:30])[CH3:29]