4-Benzylpiperidine → HCID 22350204, compound

HRID 2223219Notes

Reaction equation

HRID 2223219 reaction equation
[O:1]=[C:2]1[CH2:11][O:10][C:9]2[CH:8]=[C:7]3[NH:12][C:13]([C:15]([OH:17])=O)=[CH:14][C:6]3=[CH:5][C:4]=2[NH:3]1.[CH2:18]([CH:25]1[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>C(OCC)C>[CH2:18]([CH:25]1[CH2:30][CH2:29][N:28]([C:15]([C:13]2[NH:12][C:7]3=[CH:8][C:9]4[O:10][CH2:11][C:2](=[O:1])[NH:3][C:4]=4[CH:5]=[C:6]3[CH:14]=2)=[O:17])[CH2:27][CH2:26]1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

4

Reactant 2

HCID 317384-BenzylpiperidineHCID 223501726-Oxo-1,5,6,7-tetrahydro-8-oxa-1,5-diaza-cyclopenta[b]naphthalene-2-carboxylic acid

Product 1

HCID 22350204HCID 22350204, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from 6-oxo-1,5,6,7-tetrahydro-8-oxa-1,5-diaza-cyclopenta[b]naphthalene-2-carboxylic acid and 4-benzylpiperidine according to the method described in Example 1/c. Mp.: 225-231° C. (diethyl ether).

Sources & evidence

ORD record
ord-614c931c192d4e989c5ef9b5d27a75b5
Source dataset
uspto-grants-2008_05
Patent number
US07375116B2

Reaction notes

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