7-Amino-5-methyl-5H-dibenzo[b,d]azepin-6(7H)-one → HCID 10458337, compound

HRID 2223272Notes

Reaction equation

HRID 2223272 reaction equation
[NH2:1][CH:2]1[C:8](=[O:9])[N:7]([CH3:10])[C:6]2[CH:11]=[CH:12][CH:13]=[CH:14][C:5]=2[C:4]2[CH:15]=[CH:16][CH:17]=[CH:18][C:3]1=2.[F:19][C:20]1[CH:21]=[C:22]([CH:34]=[C:35]([F:37])[CH:36]=1)[CH2:23][NH:24][C:25](=[O:33])[CH:26]([CH2:30][CH2:31][CH3:32])[C:27](O)=[O:28]>>[F:19][C:20]1[CH:21]=[C:22]([CH:34]=[C:35]([F:37])[CH:36]=1)[CH2:23][NH:24][C:25](=[O:33])[CH:26]([CH2:30][CH2:31][CH3:32])[C:27]([NH:1][CH:2]1[C:8](=[O:9])[N:7]([CH3:10])[C:6]2[CH:11]=[CH:12][CH:13]=[CH:14][C:5]=2[C:4]2[CH:15]=[CH:16][CH:17]=[CH:18][C:3]1=2)=[O:28]

Participants

3

Reactant 2

HCID 101986267-Amino-5-methyl-5H-dibenzo[b,d]azepin-6(7H)-oneHCID 69282756HCID 69282756, compound

Product 1

HCID 10458337HCID 10458337, compound

Procedure

The title compound, MS: m/e=492.3 (M+H+), was prepared in analogy to example 16 from 7-amino-5-methyl-5H,7H-dibenzo[b,d]azepin-6-one and N-(3,5-difluoro-benzyl)-2-propyl-malonamic acid.

Sources & evidence

ORD record
ord-ea1ba588bb884cb6a5a7151558cd08b7
Source dataset
uspto-grants-2008_05
Patent number
US07375099B2

Reaction notes

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