7-Amino-5-methyl-5H-dibenzo[b,d]azepin-6(7H)-one → HCID 69282390, compound

HRID 2223274Notes

Reaction equation

HRID 2223274 reaction equation
[NH2:1][CH:2]1[C:8](=[O:9])[N:7]([CH3:10])[C:6]2[CH:11]=[CH:12][CH:13]=[CH:14][C:5]=2[C:4]2[CH:15]=[CH:16][CH:17]=[CH:18][C:3]1=2.[F:19][C:20]1[CH:21]=[C:22]([CH:35]=[C:36]([F:38])[CH:37]=1)[CH2:23][NH:24][C:25](=[O:34])[CH:26]([C:30]([CH3:33])([CH3:32])[CH3:31])[C:27](O)=[O:28]>>[C:30]([CH:26]([C:27]([NH:1][CH:2]1[C:8](=[O:9])[N:7]([CH3:10])[C:6]2[CH:11]=[CH:12][CH:13]=[CH:14][C:5]=2[C:4]2[CH:15]=[CH:16][CH:17]=[CH:18][C:3]1=2)=[O:28])[C:25]([NH:24][CH2:23][C:22]1[CH:21]=[C:20]([F:19])[CH:37]=[C:36]([F:38])[CH:35]=1)=[O:34])([CH3:33])([CH3:31])[CH3:32]

Participants

3

Reactant 2

HCID 101986267-Amino-5-methyl-5H-dibenzo[b,d]azepin-6(7H)-oneHCID 69283634HCID 69283634, compound

Product 1

HCID 69282390HCID 69282390, compound

Procedure

The title compound, MS: m/e=506.3 (M+H+), was prepared in analogy to example 16 from 7-amino-5-methyl-5H,7H-dibenzo[b,d]azepin-6-one and N-(3,5-difluoro-benzyl)-2-tert-butyl-malonamic acid.

Sources & evidence

ORD record
ord-245cba75ec4a43d1808d6c6e893137d6
Source dataset
uspto-grants-2008_05
Patent number
US07375099B2

Reaction notes

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