7-Amino-5-methyl-5H-dibenzo[b,d]azepin-6(7H)-one → HCID 10456177, compound

HRID 2223279Notes

Reaction equation

HRID 2223279 reaction equation
[NH2:1][CH:2]1[C:8](=[O:9])[N:7]([CH3:10])[C:6]2[CH:11]=[CH:12][CH:13]=[CH:14][C:5]=2[C:4]2[CH:15]=[CH:16][CH:17]=[CH:18][C:3]1=2.[F:19][C:20]1[CH:34]=[CH:33][C:23]([CH2:24][NH:25][C:26](=[O:32])[CH:27]([CH3:31])[C:28](O)=[O:29])=[CH:22][CH:21]=1>>[F:19][C:20]1[CH:34]=[CH:33][C:23]([CH2:24][NH:25][C:26](=[O:32])[CH:27]([CH3:31])[C:28]([NH:1][CH:2]2[C:8](=[O:9])[N:7]([CH3:10])[C:6]3[CH:11]=[CH:12][CH:13]=[CH:14][C:5]=3[C:4]3[CH:15]=[CH:16][CH:17]=[CH:18][C:3]2=3)=[O:29])=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 101986267-Amino-5-methyl-5H-dibenzo[b,d]azepin-6(7H)-oneHCID 44541626HCID 44541626, compound

Product 1

HCID 10456177HCID 10456177, compound

Procedure

The title compound, MS: m/e=446.2 (M+H+), was prepared in analogy to example 16 from 7-amino-5-methyl-5H,7H-dibenzo[b,d]azepin-6-one and N-(4-fluoro-benzyl)-2-methyl-malonamic acid.

Sources & evidence

ORD record
ord-fff351417e464ada8267e87f42a6add9
Source dataset
uspto-grants-2008_05
Patent number
US07375099B2

Reaction notes

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