7-Amino-5-methyl-5H-dibenzo[b,d]azepin-6(7H)-one → HCID 69282706, compound

HRID 2223283Notes

Reaction equation

HRID 2223283 reaction equation
[NH2:1][CH:2]1[C:8](=[O:9])[N:7]([CH3:10])[C:6]2[CH:11]=[CH:12][CH:13]=[CH:14][C:5]=2[C:4]2[CH:15]=[CH:16][CH:17]=[CH:18][C:3]1=2.[CH3:19][CH:20]([C:24]([NH:26][CH2:27][C:28]1[CH:33]=[C:32]([Cl:34])[CH:31]=[C:30]([Cl:35])[CH:29]=1)=[O:25])[C:21](O)=[O:22]>>[Cl:34][C:32]1[CH:33]=[C:28]([CH:29]=[C:30]([Cl:35])[CH:31]=1)[CH2:27][NH:26][C:24](=[O:25])[CH:20]([CH3:19])[C:21]([NH:1][CH:2]1[C:8](=[O:9])[N:7]([CH3:10])[C:6]2[CH:11]=[CH:12][CH:13]=[CH:14][C:5]=2[C:4]2[CH:15]=[CH:16][CH:17]=[CH:18][C:3]1=2)=[O:22]

Participants

3

Reactant 2

HCID 101986267-Amino-5-methyl-5H-dibenzo[b,d]azepin-6(7H)-oneHCID 69283591HCID 69283591, compound

Product 1

HCID 69282706HCID 69282706, compound

Procedure

The title compound, MS: m/e=496.2 (M+H+), was prepared in analogy to example 16 from 7-amino-5-methyl-5H,7H-dibenzo[b,d]azepin-6-one and 2-methyl-N-(3,5-dichloro-benzyl)-malonamic acid.

Sources & evidence

ORD record
ord-5190e85bf76d4f6fa895913015a44503
Source dataset
uspto-grants-2008_05
Patent number
US07375099B2

Reaction notes

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