3-Amino-1-methyl-5-phenyl-1H-benzo[E][1,4]diazepin-2(3H)-one → HCID 69284276, compound

HRID 2223296Notes

Reaction equation

HRID 2223296 reaction equation
[NH2:1][CH:2]1[N:8]=[C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:6]2[CH:15]=[CH:16][CH:17]=[CH:18][C:5]=2[N:4]([CH3:19])[C:3]1=[O:20].[CH3:21][CH:22]([C:26]([NH:28][CH2:29][C:30]1[CH:35]=[C:34]([Cl:36])[CH:33]=[C:32]([Cl:37])[CH:31]=1)=[O:27])[C:23](O)=[O:24]>>[Cl:36][C:34]1[CH:35]=[C:30]([CH:31]=[C:32]([Cl:37])[CH:33]=1)[CH2:29][NH:28][C:26](=[O:27])[CH:22]([CH3:21])[C:23]([NH:1][CH:2]1[C:3](=[O:20])[N:4]([CH3:19])[C:5]2[CH:18]=[CH:17][CH:16]=[CH:15][C:6]=2[C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[N:8]1)=[O:24]

Participants

3

Reactant 2

HCID 27296813-Amino-1-methyl-5-phenyl-1H-benzo[E][1,4]diazepin-2(3H)-oneHCID 69283591HCID 69283591, compound

Product 1

HCID 69284276HCID 69284276, compound

Procedure

The title compound, MS: m/e=523.3 (M+H+), was prepared in analogy to example 16 from 3-amino-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one and 2-methyl-N-(3,5-dichloro-benzyl)-malonamic acid.

Sources & evidence

ORD record
ord-5610d555ccbd40ecbadc7dc1cc718157
Source dataset
uspto-grants-2008_05
Patent number
US07375099B2

Reaction notes

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