HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-1-methyl-5-phenyl-1H-benzo[E][1,4]diazepin-2(3H)-one → 2-Methyl-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-N'-(3-trifluoromethyl-benzyl)-malonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-1-methyl-5-phenyl-1H-benzo[E][1,4]diazepin-2(3H)-one | HCID 2729681 | — |
| Reactant | HCID 69280072 | HCID 69280072 | — |
| Product | 2-Methyl-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-N'-(3-trifluoromethyl-benzyl)-malonamide | HCID 69284219 | — |
Reaction Steps
The title compound, MS: m/e=523.4 (M+H+), was prepared in analogy to example 16 from 3-amino-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one and 2-methyl-N-(3-trifluoromethyl-benzyl)-malonamic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07375099B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-a735fad7e3b949eaa0d13130c6d58353 |
| Source note | uspto-grants-2008_05 |