HCID 131726882, compound → HCID 131726881, compound

Participants

Reaction Steps

A solution of 15.26 g of alkyne 3 in 300 ml of tetrahydrofuran/methanol (3:1) is mixed with 2.7 g of palladium (10% on magnesium carbonate) and stirred at room temperature under a hydrogen atmosphere (1 bar) until the reaction is completed. For working-up, it is filtered on Celite and concentrated by evaporation in a vacuum. 15.4 g of a colorless foam 4 is obtained, which is used without further purification in the next stage (GC-MS: m/z theor.: 569, pract.: 569).

Provenance & Evidence