HCID 86597289, compound → HCID 86597291, compound

Participants

Reaction Steps

A solution of 14.36 g of tetraene 6 in 400 ml of tetrahydrofuran/methanol (3:1) is mixed with 2.8 g of palladium (10% on carbon) and stirred under a hydrogen atmosphere (100 bar) for two days at room temperature. This reaction is repeated twice. For working-up, it is filtered on Celite and concentrated by evaporation in a vacuum. The residue is purified by column chromatography (cyclohexane/ethyl acetate) and yields 8.25 g of 7 as a colorless foam (GC-MS: m/z theor.: 514, pract.: 514).

Provenance & Evidence