HCID 137329871, compound → HCID 137329873, compound

HRID 2223338Notes

Reaction equation

HRID 2223338 reaction equation
[C:1]([C@H:5]1[CH2:14][CH2:13][C@H:12]2[C@@:15]3([CH:36]=[CH2:37])[C@H:24]([C@@H:25]([CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]O)[CH2:26][C@:6]12[CH2:7][O:8][SiH:9]([CH3:11])[CH3:10])[C:23]1[CH:22]=[CH:21][C:20]([O:34][CH3:35])=[CH:19][C:18]=1[CH2:17][CH2:16]3)([CH3:4])([CH3:3])[CH3:2].C([C@H]1CC[C@H]2[C@@]3(C=C)[C@H]([C@@H](CCCCCO)C[C@]12CO[SiH](C)C)C1C=CC(OC)=CC=1CC3)(C)(C)C.[Br:74]CCCCC[C@H]1C[C@@]2(CO[SiH](C)C)[C@@H](CC[C@@H]2C(C)(C)C)[C@@]2(C=C)[C@H]1C1C=CC(OC)=CC=1CC2>>[Br:74][CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][C@H:25]1[CH2:26][C@@:6]2([CH2:7][O:8][SiH:9]([CH3:11])[CH3:10])[C@@H:12]([CH2:13][CH2:14][C@@H:5]2[C:1]([CH3:4])([CH3:2])[CH3:3])[C@@:15]2([CH:36]=[CH2:37])[C@H:24]1[C:23]1[CH:22]=[CH:21][C:20]([O:34][CH3:35])=[CH:19][C:18]=1[CH2:17][CH2:16]2

Participants

4

Reactant 3

HCID 137329871HCID 137329871, compoundHCID 137329872HCID 137329872, compoundHCID 137329874HCID 137329874, compound

Product 1

HCID 137329873HCID 137329873, compound

Procedure

The reaction of 930 mg of alcohol 12 is carried out analogously to the test instructions for the conversion of alcohol 8 into bromide 10. In this way, 975 mg of bromide 13 is obtained as a colorless, viscous oil (GC-MS: m/z theor.: 588, pract.: 588).

Sources & evidence

ORD record
ord-2876fa61b6be4d1f808d3a4404e9ce20
Source dataset
uspto-grants-2008_05
Patent number
US07375098B2

Reaction notes

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