HRID2223343

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11205884

Silane, trimethyl(trifluoroethenyl)-

C5H9F3Si

结构：C=C[C@@]12CCc3cc(OC)ccc3[C@H]1[C@@H](CCCCC=O)C[C@]1(C)[C@@H](O[Si](C)(C)C(C)(C)C)CC[C@H]12

HCID12136519

未命名化合物

PRODUCTS

生成物

结构：C=C[C@@]12CCc3cc(OC)ccc3[C@H]1[C@@H](CCCCC(O[Si](C)(C)C)C(F)=C(F)F)C[C@]1(C)[C@@H](O[Si](C)(C)C(C)(C)C)CC[C@H]12

HCID131726885

未命名化合物

PROCEDURE

实验过程

In the reaction with 1,1,2-trifluoro-2-trimethylsilyl ethylene analogously to instructions 1.1, 60 mg of aldehyde 9a yields 77 mg of trimethylsilyl ether 23a as a colorless foam (GC-MS: m/z theor.: 664, pract.: 664) and a mixture of its diastereomers. The latter is used without further purification in the next stage.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-bd4833a20d724afcb7e88c80bf3f206d
来源数据集: uspto-grants-2008_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07375098B2
来源说明: uspto-grants-2008_05

反应 SMILES

[F:1][C:2]([F:9])=[C:3]([F:8])[Si](C)(C)C.[Si:10]([O:17][C@H:18]1[CH2:23][CH2:22][C@H:21]2[C@@:24]3([CH:44]=[CH2:45])[C@H:33]([C@@H:34]([CH2:36][CH2:37][CH2:38][CH2:39][CH:40]=[O:41])[CH2:35][C@:19]12[CH3:20])[C:32]1[CH:31]=[CH:30][C:29]([O:42][CH3:43])=[CH:28][C:27]=1[CH2:26][CH2:25]3)([C:13]([CH3:16])([CH3:15])[CH3:14])([CH3:12])[CH3:11]>>[Si:10]([O:17][C@H:18]1[CH2:23][CH2:22][C@H:21]2[C@@:24]3([CH:44]=[CH2:45])[C@H:33]([C@@H:34]([CH2:36][CH2:37][CH2:38][CH2:39][CH:40]([O:41][Si:10]([CH3:13])([CH3:12])[CH3:11])[C:3]([F:8])=[C:2]([F:9])[F:1])[CH2:35][C@:19]12[CH3:20])[C:32]1[CH:31]=[CH:30][C:29]([O:42][CH3:43])=[CH:28][C:27]=1[CH2:26][CH2:25]3)([C:13]([CH3:16])([CH3:15])[CH3:14])([CH3:11])[CH3:12]