HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 11beta-[5-(Methylamino)pentyl]-8-vinylestra-1,3,5(10)-triene-3,17beta-diol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 11beta-(5-Bromopentyl)-8-vinyl-estra-1,3,5(10)-triene-3,17beta-diol | HCID 12136541 | — |
| Product | 11beta-[5-(Methylamino)pentyl]-8-vinylestra-1,3,5(10)-triene-3,17beta-diol | HCID 12136542 | — |
Reaction Steps
In the reaction with methylamine (40% in water, 2 ml/mmol) analogously to instructions 17.2, 258 mg of bromide 30a yields 161 mg of amine 31a as a colorless solid (GC-MS: m/z theor.: 397, pract.: 397).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07375098B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-9c565c91a6344fbfaea507a32a2286c1 |
| Source note | uspto-grants-2008_05 |