HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → 11beta-[5-(Dimethylamino)pentyl]-8-vinylestra-1,3,5(10)-triene-3,17beta-diol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 11beta-(5-Bromopentyl)-8-vinyl-estra-1,3,5(10)-triene-3,17beta-diol | HCID 12136541 | — |
| Product | 11beta-[5-(Dimethylamino)pentyl]-8-vinylestra-1,3,5(10)-triene-3,17beta-diol | HCID 12136543 | — |
Reaction Steps
In the reaction with dimethylamine (2 M in tetrahydrofuran, 10 equivalents) analogously to instructions 17.2, 30 mg of bromide 30a yields 12 mg of amine 32a as a colorless foam (GC-MS: m/z theor.: 411, pract.: 411).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07375098B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-72d67df3a32f457c9ae490d5888d3231 |
| Source note | uspto-grants-2008_05 |