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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2223347Generated: October 31, 2026

Morpholine → 11beta-(5-Morpholinopentyl)-8-vinylestra-1,3,5(10)-triene-3,17beta-diol

https://huagongshe.com/reaction/2223347

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant11beta-(5-Bromopentyl)-8-vinyl-estra-1,3,5(10)-triene-3,17beta-diolHCID 12136541—
Product11beta-(5-Morpholinopentyl)-8-vinylestra-1,3,5(10)-triene-3,17beta-diolHCID 12136546—

Reaction Steps

In the reaction with morpholine (10 equivalents) analogously to instructions 17.2, 30 mg of bromide 30a yields 10 mg of amine 35a as a colorless foam (GC-MS: m/z theor.: 453, pract.: 453).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07375098B2
Source datasetuspto-grants-2008_05
ORD IDord-58a4527b4c67489e9e1885d207f7bbac
Source noteuspto-grants-2008_05