HCID 12137007, compound → HCID 12137012, compound

HRID 2223354Notes

Reaction equation

HRID 2223354 reaction equation
S(C1C=CC(C)=CC=1)(O[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([F:18])([F:17])[C:13]([F:16])([F:15])[F:14])(=O)=O.[CH3:26][NH:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][C@H:34]1[CH2:51][C@@:49]2([CH3:50])[C@@H:45]([CH2:46][CH2:47][C@@H:48]2[OH:52])[C@@:44]2([CH:53]=[CH2:54])[C@H:35]1[C:36]1[CH:37]=[CH:38][C:39]([OH:55])=[CH:40][C:41]=1[CH2:42][CH2:43]2>>[CH3:26][N:27]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([F:17])([F:18])[C:13]([F:14])([F:15])[F:16])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][C@H:34]1[CH2:51][C@@:49]2([CH3:50])[C@@H:45]([CH2:46][CH2:47][C@@H:48]2[OH:52])[C@@:44]2([CH:53]=[CH2:54])[C@H:35]1[C:36]1[CH:37]=[CH:38][C:39]([OH:55])=[CH:40][C:41]=1[CH2:42][CH2:43]2

Participants

3

Reactant 2

HCID 12137007HCID 12137007, compoundHCID 15858643HCID 15858643, compound

Product 1

HCID 12137012HCID 12137012, compound

Procedure

In the reaction with 8,8,9,9,9-pentafluorononyl tosylate analogously to instructions 22.1, 39 mg of amine 31b yields 22 mg of amine 36b as a colorless foam (GC-MS: m/z theor.: 627, pract.: 627).

Sources & evidence

ORD record
ord-d25ba4180bd74994b81c1d9962ff6596
Source dataset
uspto-grants-2008_05
Patent number
US07375098B2

Reaction notes

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