Methanol → HCID 86622591, compound

HRID 2223438Notes

Reaction equation

HRID 2223438 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]([S:11]([F:16])([F:15])([F:14])([F:13])[F:12])[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].O=S(Cl)Cl.[CH3:21]O>>[Cl:1][C:2]1[CH:10]=[C:9]([S:11]([F:16])([F:12])([F:13])([F:14])[F:15])[CH:8]=[CH:7][C:3]=1[C:4]([O:6][CH3:21])=[O:5]

Participants

4

Reactant 3

HCID 887MethanolHCID 24386Thionyl ChlorideHCID 86622590HCID 86622590, compound

Product 1

HCID 86622591HCID 86622591, compound

Procedure

4.3 g of 2-chloro-4-pentafluorosulfanylbenzoic acid were dissolved in 50 ml of methanol and, at RT, 5.6 ml of SOCl2 were slowly added dropwise. After boiling under reflux for 6 hours and removal of the volatile constituents in vacuo, the residue was taken up in 100 ml of toluene, and the volatile constituents were again removed in vacuo. 4.1 g of a colorless oil were obtained.

Workup

  1. temperatureunder reflux for 6 hours
  2. customremoval of the volatile constituents in vacuo
  3. customthe volatile constituents were again removed in vacuo

Sources & evidence

ORD record
ord-5b0be93b5da240cb86fa973ceeca1c3c
Source dataset
uspto-grants-2008_05
Patent number
US07375138B2

Reaction notes

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