Morpholine → 5-(Methanesulfonyl)-2-(morpholin-4-yl)benzoic acid

HRID 2223489Notes

Reaction equation

HRID 2223489 reaction equation
Cl[C:2]1[CH:10]=[CH:9][C:8]([S:11]([CH3:14])(=[O:13])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[NH:15]1[CH2:20][CH2:19][O:18][CH2:17][CH2:16]1>>[CH3:14][S:11]([C:8]1[CH:9]=[CH:10][C:2]([N:15]2[CH2:20][CH2:19][O:18][CH2:17][CH2:16]2)=[C:3]([CH:7]=1)[C:4]([OH:6])=[O:5])(=[O:13])=[O:12]

Participants

3

Reactant 2

HCID 8083MorpholineHCID 23291322-Chloro-5-(methylsulphonyl)benzoic acid

Product 1

HCID 211003195-(Methanesulfonyl)-2-(morpholin-4-yl)benzoic acid

Procedure

Prepared in analogy to example B from 2-chloro-5-methanesulfonyl-benzoic acid and morpholine. MS (m/e):284.1 (MH−, 100%).

Sources & evidence

ORD record
ord-64c59a4b9d454b4891656c32eaeef343
Source dataset
uspto-grants-2008_05
Patent number
US07375226B2

Reaction notes

Loading…