6-Chloro-1,2,3,4-tetrahydro(1)benzothieno(2,3-c)pyridine → HCID 11497253, compound

HRID 2223499Notes

Reaction equation

HRID 2223499 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:14][C:9]3[CH2:10][NH:11][CH2:12][CH2:13][C:8]=3[C:6]=2[CH:7]=1.[CH3:15][S:16]([C:19]1[CH:20]=[CH:21][C:22]([O:28][C@@H:29]([CH3:34])[C:30]([F:33])([F:32])[F:31])=[C:23]([CH:27]=1)[C:24](O)=[O:25])(=[O:18])=[O:17]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:14][C:9]3[CH2:10][N:11]([C:24]([C:23]4[CH:27]=[C:19]([S:16]([CH3:15])(=[O:17])=[O:18])[CH:20]=[CH:21][C:22]=4[O:28][C@@H:29]([CH3:34])[C:30]([F:32])([F:33])[F:31])=[O:25])[CH2:12][CH2:13][C:8]=3[C:6]=2[CH:7]=1

Participants

3

Reactant 2

HCID 2831816-Chloro-1,2,3,4-tetrahydro(1)benzothieno(2,3-c)pyridineHCID 58863351(S)-2-(1-Methyl-2,2,2-trifluoroethoxy)-5-methylsulfonylbenzoic acid

Product 1

HCID 11497253HCID 11497253, compound

Procedure

The title compound was prepared in analogy to Example 1 using 6-chloro-1,2,3,4-tetrahydro-[1]benzothieno[2,3-c]pyridine [29078-50-0] and 5-methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]benzoic acid [845616-82-2]. MS (m/e): 518.1 (M+H+).

Sources & evidence

ORD record
ord-81e907398d514878996d6b3f886472b6
Source dataset
uspto-grants-2008_05
Patent number
US07375226B2

Reaction notes

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