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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2223593Generated: October 30, 2026

Glycinamide hydrochloride → 4-[(4-{3-[1-Carbamoyl-1-(methyl)-ethylcarbamoyl]propyl}phenyl)methyl]-3-(beta-D-galactopyranosyloxy)-5-isopropyl-1H-pyrazole

https://huagongshe.com/reaction/2223593

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycinamide hydrochlorideHCID 2723639—
Reactant2-Amino-2-methylpropanamideHCID 6453783—
ReactantHCID 68537679HCID 68537679—
Product4-[(4-{3-[1-Carbamoyl-1-(methyl)-ethylcarbamoyl]propyl}phenyl)methyl]-3-(beta-D-galactopyranosyloxy)-5-isopropyl-1H-pyrazoleHCID 68535822—

Reaction Steps

The title compound was prepared in a similar manner to that described in Example 1 using 3-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyloxy)-4-({4-[(1E)-3-carboxyprop-1-enyl]-phenyl}methyl)-5-isopropyl-1H-pyrazole and 2-amino-2-methylpropionamide instead of 3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)-4-({4-[(1E)-3-carboxyprop-1-enyl]-phenyl}methyl)-5-isopropyl-1H-pyrazole and glycinamide hydrochloride, respectively.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07375087B2
Source datasetuspto-grants-2008_05
ORD IDord-b0510878221444bbad416939d3bf23e5
Source noteuspto-grants-2008_05