HRID2223606

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6581

Acrylic acid

C3H4O2

HCID32743

3-Butenoic acid

C4H6O2

结构：CC(=O)OC[C@H]1O[C@@H](Oc2n[nH]c(C(C)C)c2Cc2ccc(Br)cc2C)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

HCID68537680

未命名化合物

PRODUCTS

生成物

结构：CC(=O)OC[C@H]1O[C@@H](Oc2n[nH]c(C(C)C)c2Cc2ccc(/C=C/C(=O)O)cc2C)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

HCID68537852

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in a similar manner to that described in Reference Example 4 using 3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)-4-[(4-bromo-2-methylphenyl)methyl]-5-isopropyl-1H-pyrazole and acrylic acid instead of 3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)-4-[(4-bromophenyl)methyl]-5-isopropyl-1H-pyrazole and 3-butenoic acid, respectively.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ba92792845a344328f629a2c8d296064
来源数据集: uspto-grants-2008_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07375087B2
来源说明: uspto-grants-2008_05

反应 SMILES

[C:1]([O:4][C@@H:5]1[C@@H:10]([O:11][C:12](=[O:14])[CH3:13])[C@H:9]([O:15][C:16](=[O:18])[CH3:17])[C@@H:8]([CH2:19][O:20][C:21](=[O:23])[CH3:22])[O:7][C@H:6]1[O:24][C:25]1[C:29]([CH2:30][C:31]2[CH:36]=[CH:35][C:34](Br)=[CH:33][C:32]=2[CH3:38])=[C:28]([CH:39]([CH3:41])[CH3:40])[NH:27][N:26]=1)(=[O:3])[CH3:2].[C:42]([OH:46])(=[O:45])[CH:43]=[CH2:44].C(O)(=O)CC=C>>[C:1]([O:4][C@@H:5]1[C@@H:10]([O:11][C:12](=[O:14])[CH3:13])[C@H:9]([O:15][C:16](=[O:18])[CH3:17])[C@@H:8]([CH2:19][O:20][C:21](=[O:23])[CH3:22])[O:7][C@H:6]1[O:24][C:25]1[C:29]([CH2:30][C:31]2[CH:36]=[CH:35][C:34](/[CH:44]=[CH:43]/[C:42]([OH:46])=[O:45])=[CH:33][C:32]=2[CH3:38])=[C:28]([CH:39]([CH3:41])[CH3:40])[NH:27][N:26]=1)(=[O:3])[CH3:2]