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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2223614Generated: November 1, 2026

Tris(hydroxymethyl)aminomethane → HCID 68538726, compound

https://huagongshe.com/reaction/2223614

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTris(hydroxymethyl)aminomethaneHCID 6503—
Reactant1-(2-Hydroxyethyl)piperazineHCID 7677—
ReactantHCID 68537520HCID 68537520—
ProductHCID 68538726HCID 68538726—

Reaction Steps

The title compound was prepared in a similar manner to that described in Example 48 using 3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)-4-[(4-{3-[1-carboxy-1-(methyl)-ethylcarbamoyl]propyl}phenyl)methyl]-5-isopropyl-1H-pyrazole and tris(hydroxymethyl)aminomethane instead of 3-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyloxy)-4-[(4-{3-[1-carboxy-1-(methyl)-ethylcarbamoyl]propyl}phenyl)methyl]-5-isopropyl-1H-pyrazole and 1-(2-hydroxyethyl)-piperazine, respectively.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07375087B2
Source datasetuspto-grants-2008_05
ORD IDord-bdbe0b4f04904e1d830d68ef2809a896
Source noteuspto-grants-2008_05