HCID 59715925, compound → HCID 17956460, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 4-(3-methyl-benzylidene)-piperidine-1-carboxylic acid tert-butyl ester (287.4 mg, 1 mmol) in CH2Cl2 (1 mL) TFA (1 mL) is added. The solution is stirred for 2 h at 20° C. The solvent is evaporated, the residue dissolved CH2Cl2 (75 mL) and washed with 1 M aqueous NaOH (2×20 mL). The organic layer is dried (Na2SO4), filtered and concentrated to provide the title compound.

Provenance & Evidence